MAPK signaling pathway-targeted marine compounds in cancer therapy.

ABSTRACT:

Purpose

This paper reviews marine compounds that target the mitogen-activated protein kinase (MAPK) signaling pathway and their main sources, chemical structures, major targeted cancers and possible mechanisms to provide comprehensive and basic information for the development of marine compound-based antitumor drugs in clinical cancer therapy research.

Methods

This paper searched the PubMed database using the keywords "cancer", "marine*" and "MAPK signaling pathway"; this search was supplemented by the literature-tracing method. The marine compounds screened for review in this paper are pure compounds with a chemical structure and have antitumor effects on more than one tumor cell line by targeting the MAPK signaling pathway. The PubChem database was used to search for the P

SUBMITTER: Wei J 

PROVIDER: S-EPMC11801988 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature