Mammographic Density in Relation to Breast Cancer Risk Factors among Chinese Women.

ABSTRACT:

Background

Increased mammographic density (MD) is a known breast cancer risk factor, but its influencing factors are unclear in Asian populations. This study examined the links between known breast cancer risk factors and quantitatively measured MD in 7,351 Chinese women with nonmalignant mammographic findings.

Methods

VolparaDensity software quantified volumetric MD measures: total breast volume (TBV), absolute dense volume (ADV), percent dense volume (PDV = ADV/TBV), and nondense volume (NDV = TBV - ADV). Multivariable linear regression models assessed associations between these MD metrics and breast cancer risk factors.

Results

The mean age of the population was 50.1 (SD = 8.3) years. The mean ADV, NDV, and PDV were 58.4 cm3 (SD = 32.1), 382.8 cm3 (SD = 202.0), and

SUBMITTER: Koka H 

PROVIDER: S-EPMC11802310 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature