Case report: A panorama gene profile of ovarian cancer metastasized to axillary lymph node.

ABSTRACT:

Background

Ovarian cancer is among the most lethal gynecologic malignancies, with a high proportion of patients diagnosed at advanced stages, leading to poor survival outcomes. Axillary lymph node metastasis from ovarian cancer is extremely rare and the mechanism is still unclear.

Methods

A comprehensive set of clinical and gynecologic oncology assessments were performed, including ultrasound, mammography, MRI, transvaginal ultrasound, and tissue staining. To unravel the carcinogenesis, the next-generation sequencing (NGS) was performed.

Results

Conventional examinations and imaging suggested the presence of both occult breast cancer and ovarian cancer. However, immunohistochemical staining confirmed the diagnosis of high-grade serous ovarian carcinoma. Further analys

SUBMITTER: Xia Y 

PROVIDER: S-EPMC11802514 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature