Systematic review of multidrug-resistant <i>Klebsiella pneumoniae</i> in the Arabian Peninsula: molecular epidemiology and resistance patterns.

ABSTRACT:

Background

The rapid emergence of multidrug-resistant Klebsiella pneumoniae (MDR K. pneumoniae) is a major public health and economic burden worldwide. Various resistance mechanisms complicate treatment, leading to increased morbidity and mortality. Despite numerous studies conducted in Gulf Health Council (GHC) countries, the molecular epidemiology of MDR K. pneumoniae remains not clearly defined. This systematic review aims to analyze the emergence of antimicrobial resistance genes in MDR K. pneumoniae across GHC countries.

Methods

A systematic search was conducted using PubMed, ScienceDirect, and OpenMD for articles published up to March 15, 2023. The search strategy focused on the bacterial name, drug-resistance genotypes, and GHC countries. T

SUBMITTER: Idrees EK 

PROVIDER: S-EPMC11802542 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature