Are white matter hyperintensities associated with neuroborreliosis? The answer is twofold.

ABSTRACT:

Purpose

Many consider white matter hyperintensities (WMHs) to be important imaging findings in neuroborreliosis. However, evidence regarding association with WMHs is of low quality. The objective was to investigate WMHs in neuroborreliosis visually and quantitatively.

Materials and methods

Patients underwent brain MRI within one month of diagnosis and six months after treatment. Healthy controls were recruited. WMHs were counted by visual rating and the volume was calculated from automatic segmentation. Biochemical markers and scores for clinical symptoms and findings were used to explore association with longitudinal volume change of WMHs.

Results

The study included 74 patients (37 males) with early neuroborreliosis and 65 controls (30 males). Mean age (standard devi

SUBMITTER: Lindland ES 

PROVIDER: S-EPMC11802615 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature