Transcriptomic Signature of Lipid Production in Australian Aurantiochytrium sp. TC20.

ABSTRACT: Aurantiochytrium not only excels in producing long-chain polyunsaturated fatty acids such as docosahexaenoic acid for humans, but it is also a source of essential fatty acids with minimal impacts on wild fisheries and is vital in the transfer of atmospheric carbon to oceanic carbon sinks and cycles. This study aims to unveil the systems biology of lipid production in the Australian Aurantiochytrium sp. TC20 by comparing the transcriptomic profiles under optimal growth conditions with increased fatty acid production from the early (Day 1) to late exponential growth phase (Day 3). Particular attention was paid to 227 manually annotated genes involved in lipid metabolism, such as FAS (fatty acid synthetase) and subunits of polyunsaturated fatty acids (PUFA) synthase. PCA analysis showed that

SUBMITTER: Lee Chang KJ 

PROVIDER: S-EPMC11802676 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature