Examining tolerability, safety, and blinding in 1032 transcranial electrical stimulation sessions for children and adolescents with neuropsychiatric and neurodevelopmental disorders.

ABSTRACT: The present study first extensively evaluated the tolerability, safety, and blinding of transcranial direct current stimulation (tDCS) and transcranial random noise stimulation (tRNS) in paediatric clinical populations, composed of 92 children and adolescents (54 females, age range: 8-17 years), involving 1032 sessions across neuropsychiatric (i.e., anorexia nervosa) and neurodevelopmental (i.e., attention deficit and hyperactivity disorder, developmental dyscalculia) conditions. It compared adverse events (AEs) occurrence between active and sham transcranial electrical stimulation (tES) conditions (i.e., 528 active vs. 504 sham sessions) as well as tDCS and tRNS (i.e., 772 tDCS sessions vs. 260 tRNS sessions), while considering demographic and emotional-behavioural factors. Results showed

SUBMITTER: Battisti A 

PROVIDER: S-EPMC11802757 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature