Pathogenic and periodontal bacteria may contribute to the fatal outcome of critically ill elderly COVID-19 patients.

ABSTRACT: Some studies suggest that the respiratory microbiome of COVID-19 patients differs from that of healthy individuals, infected patients may have reduced diversity and increased levels of opportunistic bacteria, however, the role of the microbiome in fatal SARS-CoV-2 infection remains poorly understood. Our study aimed to determine whether there are differences in the respiratory microbiome between patients who recovered from COVID-19 and those who died, by characterizing the bacterial communities of both groups. A total of 24 patients who recovered from COVID-19 and 24 who died were included in the study, patient data were analyzed for signs, symptoms and clinical variables. Airway samples were collected and the 16 S rRNA variable regions V3-V4 were amplified and sequenced using the Illumina

SUBMITTER: Madronero LJ 

PROVIDER: S-EPMC11802917 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature