Mechanical Properties of the Cortex in Older Adults and Relationships With Personality Traits.

ABSTRACT: Aging and neurodegeneration impact structural brain integrity and can result in changes to behavior and cognition. Personality, a relatively stable trait in adults as compared to behavior, in part relies on normative individual differences in cellular organization of the cerebral cortex, but links between brain structure and personality expression have been mixed. One key finding is that personality has been shown to be a risk factor in the development of Alzheimer's disease, highlighting a structure-trait relationship. Magnetic resonance elastography (MRE) has been used to noninvasively study age-related changes in tissue mechanical properties because of its high sensitivity to both the microstructural health and the structure-function relationship of the tissue. Recent advancements in MR

SUBMITTER: Twohy KE 

PROVIDER: S-EPMC11803078 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature