Urine exosome biomarkers of obesity after Lekhana Basti treatment - Report of a pilot study.

ABSTRACT:

Background

Obesity is a rising risk factor for various diseases including cardiovascular diseases and Cancer. The limitations of targeted obesity-treatment approaches employed in the clinic presently underscore the importance of developing integrative management strategies for identification of specific biomarkers of obesity.

Objectives

Given the specificity of exosome/extracellular vesicle (EV) biomarkers, we aimed here to identify the EV biomarkers of Ayurveda treatment - Lekhana Basti - for Obesity.

Methodology

A total of eighteen 24-h urine samples from 6 participants with BMI>30 kg/m² were used in this study, collected over 3 time-points during the Lekhana basti (medicated enema for obesity) treatment. Urine EV were isolated using Polyethylene Glycol (

SUBMITTER: Vijay B 

PROVIDER: S-EPMC11803157 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature