⁶⁸Ga-pentixafor PET/CT in guiding surgical management of primary aldosteronism.

ABSTRACT:

Purpose

This study aimed to explore the significance of ⁶⁸Ga-pentixafor PET/CT in guiding surgical treatments for primary aldosteronism (PA) patients, by identifying functional lesions and determining the dominant side of aldosterone secretion.

Materials and methods

We prospectively included 91 PA patients receiving surgical treatments based on the results of ⁶⁸Ga-pentixafor PET/CT. The ⁶⁸Ga-pentixafor PET/CT images were evaluated by visual and semi-quantitative analysis. The relationship between radionuclide imaging characteristics and postoperative outcomes was assessed following surgery.

Results

The positive detection rate of ⁶⁸Ga-pentixafor PET/CT in 91 PA patients was 85.7 % (78/91) with a median maximum standardized up

SUBMITTER: Zheng G 

PROVIDER: S-EPMC11803161 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature