Survival improvement over time in renal cell carcinoma treated with nephrectomy: A longitudinal propensity score-matched study.

ABSTRACT:

Objective

Surgical treatment for renal cell carcinoma (RCC) has drastically evolved for the past 30 years. However, survival outcomes of RCC according to times have not been fully elucidated, especially in the real-world setting. This study aimed to assess the survival improvement over time in RCC treated with nephrectomy by analyzing a longitudinal cohort using propensity score matching (PSM).

Methods

We retrospectively reviewed 960 patients with RCC who underwent radical or partial nephrectomy between 1981 and 2018. Patients were divided into two groups according to the time of surgery (1981-1999 vs. 2000-2018). Using PSM, overall survival (OS), cancer-specific survival (CSS), and recurrence-free survival (RFS) were compared between the two groups.

Results

Overall,

SUBMITTER: Kishitani K 

PROVIDER: S-EPMC11803181 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature