Verbal paired associates learning lateralizes left hippocampal sclerosis in temporal lobe epilepsy.

ABSTRACT:

Objective

Left hippocampal sclerosis (HS) is associated with verbal-specific memory impairment. This association is well established for word list learning tasks, and there is some evidence that this may also be relevant to verbal paired associates learning (PAL), though the evidence is limited. We aimed to evaluate the utility of verbal PAL as a marker for left HS, compare this with word list learning, and derive cutoff scores to facilitate clinical application.

Methods

Retrospective analysis of Rey Auditory Verbal Learning Test (RAVLT) and PAL scores obtained from 116 surgically naïve temporal lobe epilepsy patients with HS (14 bilateral, 57 left, 45 right; range of N across test indices: 77-110).

Results

Relative to right HS, left HS and bilateral HS were associate

SUBMITTER: Sitoh A 

PROVIDER: S-EPMC11803290 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature