Line-field confocal optical coherence tomography in lichen planopilaris and frontal fibrosing alopecia: A pilot study.

ABSTRACT:

Background and objectives

Lichen planopilaris (LPP) and frontal fibrosing alopecia (FFA) are common causes of cicatricial alopecia. While several studies have demonstrated the usefulness of non-invasive imaging methods such as reflectance confocal microscopy (RCM) and optical coherence tomography (OCT) for the diagnosis of scarring alopecia, this study aimed to identify characteristic features of cicatricial alopecia in LPP/FFA using line-field confocal OCT (LC-OCT).

Patients and methods

Fifty-one patients (26 LPP, 24 FFA, 1 LPP and FFA) were prospectively analyzed with LC-OCT at three defined locations on the scalp: (1) scarring area = lesion, (2) scar-hair boundary = transition zone and (3) healthy area for the presence of the following pre-defined criteria: no hair follic

SUBMITTER: Nutz MC 

PROVIDER: S-EPMC11803347 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature