Exposure to Dengue Virus During Pregnancy: Incidence and Impact on Maternal and Child Outcomes.

ABSTRACT: Dengue virus (DENV) is the most common arbovirus globally, with its incidence growing dramatically in recent decades. Although the effects of DENV infection during pregnancy are unclear, reported associations with adverse health outcomes include miscarriage, prematurity, and low birth weight. In this study, we used an IgG ELISA to identify mothers exposed to DENV during pregnancy by testing samples obtained from a previous study that followed a cohort of pregnant women in Kenya to investigate parasitic infections during pregnancy. We compared adverse pregnancy and infant health outcomes between seronegative mothers and those who seroconverted. Of the 289 participants tested for DENV exposure during pregnancy, we estimated that ∼12 women (4%) would have been exposed to DENV during their ges

SUBMITTER: Smith A 

PROVIDER: S-EPMC11803650 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature