Associations between work characteristics and osteoarthritis: A cross-sectional study of 285,947 UK Biobank participants.

ABSTRACT:

Objectives

Shift work-induced circadian rhythm disruption has been identified as a risk factor for specific diseases. Additionally, physically demanding work has been linked to osteoarthritis. This study investigated the independent associations of shift work and physical work with risk of osteoarthritis.

Design

UK Biobank participants completed questionnaires detailing their employment status, including shift work, night shifts, heavy manual work and prolonged non-sedentary work. Responses were categorised into binary and categorical variables. Knee and hip osteoarthritis diagnoses were extracted from hospital records and osteoarthritis (any site) was self-reported. Logistic regression models, adjusted for age, sex, BMI, Townsend Deprivation Index and other work factors, we

SUBMITTER: Hashmi A 

PROVIDER: S-EPMC11803847 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature