Genetics and biological characteristics of duck reoviruses isolated from ducks and geese in China.

ABSTRACT: The emergence and circulation of duck reovirus have caused severe threats to domestic waterfowl production because of the lethal infections they cause in ducks and geese. However, the evolution of circulating duck reoviruses and their replication and pathogenicity in domestic birds have not been fully investigated. In this study, we identified and isolated six duck reoviruses from clinical samples of sick or deceased farmed ducks and geese and sequenced their full genomes. Phylogenetic analysis revealed the evolutionary landscape of duck reoviruses and the complex reassortment of these circulating viruses with avian orthoreovirus and Muscovy duck reovirus. Animal infection studies revealed differences in the replication and pathogenicity of the reoviruses identified in this study in ducks,

SUBMITTER: Sun X 

PROVIDER: S-EPMC11803967 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature