Pre-diagnostic risk factors for brain cancer incidence and survival: insights from the Golestan Cohort Study.

ABSTRACT:

Background

Brain cancer is an important public health concern in terms of its burden and the cost of its treatment. Evidence on determinants of brain cancer incidence and survival are sparse and inconsistent. We aimed to explore the pre-diagnostic factors for brain cancer incidence and survival in northeastern Iran.

Methods

Data for the current study were derived from the Golestan Cohort Study, the largest cohort study in the Middle East on over 50,000 participants aged 40 to 75 years with a median follow-up of 15 years. Minimally adjusted and multiple Cox proportional hazards models were used to investigate the association of demographic and behavioral risk factors with brain cancer incidence and survival.

Results

Out of the 49,783 cancer free participants recruited

SUBMITTER: Rezanejad-Asl P 

PROVIDER: S-EPMC11804039 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature