Vitamin and herbal supplements' use among patients with advanced gastrointestinal cancers included in eight clinical trials.

ABSTRACT:

Objective

To evaluate the patterns of vitamin and herbal supplement use among patients with advanced gastrointestinal (GI) cancers and the association of such behavior with the efficacy and toxicity of systemic anticancer treatment.

Methods

Project data sphere (PDS) was used to access de-identified datasets of eight clinical trials of advanced GI cancers. Multivariable logistic regression analysis was used to identify factors predicting the use of supplements. Kaplan-Meier survival estimates were used to evaluate the association of supplement use with overall and progression-free survival. Results were stratified according to the site of the primary tumor [pancreatic, gastric, colorectal or hepatocellular carcinoma (HCC)] The association between supplement use and selected c

SUBMITTER: Abdel-Rahman O 

PROVIDER: S-EPMC11804426 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature