Efficacy of fish oil supplementation on metabolic dysfunction-associated steatotic liver disease: a meta-analysis.

ABSTRACT:

Objective

Globally, the occurrence of Metabolic dysfunction-associated steatotic liver disease (MASLD) is on a steady rise. Fish oil has anti-inflammatory effects and can improve lipid metabolism. The article aims to assess the impact of fish oil supplementation on MASLD.

Methods

We conducted a systematic search of Cochrane, Embase, PubMed, and Web of Science up to September 31, 2024, for randomized control trials (RCTs). The risk of bias of the included RCTs was evaluated using the Cochrane Collaboration's tool. Outcomes measured were aspects of liver injury, lipid profile, insulin resistance, anthropometric measurements, and more.

Results

Seven randomized controlled trials (RCTs) involving 439 participants were incorporated into the analysis. In general, the risk of

SUBMITTER: Zhou L 

PROVIDER: S-EPMC11804523 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature