PH-responsive molybdenum disulphide composite nanomaterials for skin wound healing using "ROS leveraging" synergistic immunomodulation.

ABSTRACT: With the increasing prevalence of drug-resistant bacterial infections, wound bacterial infections have evolved into an escalating medical problem that poses a threat to the individual health as well as global public health. Traditional drug therapy not only suffers from a single treatment method, low drug utilisation and limited therapeutic effect, but long-term antibiotic abuse has significantly increased bacterial resistance. It is imperative to develop an antibiotic-free biomaterial with antibacterial and anti-inflammatory properties. The current use of photothermal therapy (PTT) and photodynamic therapy (PDT) relies on the generation of massive reactive oxygen species (ROS), which inevitably aggravates the inflammatory response. Herein, we developed AuAg bimetallic nanoparticles based

SUBMITTER: Yang Z 

PROVIDER: S-EPMC11804827 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature