Network analysis of neuropsychiatric, cognitive, and functional complications of stroke: implications for novel treatment targets.

ABSTRACT:

Aim

Recovery from stroke is adversely affected by neuropsychiatric complications, cognitive impairment, and functional disability. Better knowledge of their mutual relationships is required to inform effective interventions. Network theory enables the conceptualization of symptoms and impairments as dynamic and mutually interacting systems. We aimed to identify interactions of poststroke complications using network analysis in diverse stroke samples.

Methods

Data from 2185 patients were sourced from member studies of STROKOG (Stroke and Cognition Consortium), an international collaboration of stroke studies. Networks were generated for each cohort, whereby nodes represented neuropsychiatric symptoms, cognitive deficits, and disabilities on activities of daily living. Edges c

SUBMITTER: Oestreich LKL 

PROVIDER: S-EPMC11804916 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature