Initial treatment choices for long-term remission of chronic insomnia disorder in adults: a systematic review and network meta-analysis.

ABSTRACT:

Background

We aimed to evaluate the comparative efficacy and acceptability of cognitive behavioral therapy for insomnia (CBT-I), pharmacotherapy, and their combination in the long and short terms among adults with chronic insomnia disorder.

Methods

We searched multiple databases to December 27, 2023. We included trials in hypnotic-free adults with chronic insomnia comparing at least two of CBT-I, pharmacotherapy, or their combination. We assessed the confidence in evidence using CINeMA. The primary outcome was long-term remission. Secondary outcomes included all-cause dropout and self-reported sleep continuity measures in the long term, and the same outcomes in the short term. We performed frequentist random-effects network meta-analyses (CRD42024505519).

Findings

We

SUBMITTER: Furukawa Y 

PROVIDER: S-EPMC11804918 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature