A soft multimodal optoelectronic array interface for multiparametric mapping of heart function in vivo.

ABSTRACT: Multiparametric investigation of cardiac physiology is crucial for the diagnosis and therapy of heart disease. However, no method exists to simultaneously map multiple parameters that govern cardiac (patho)physiology from beating hearts in vivo. Here, we present a cardiac sensing platform that addresses this challenge, functioning with a wireless interface. Advanced fabrication and assembling strategies enable the heterogeneous integration of transparent microelectrodes, light-emitting diodes, photodiodes, and optical filters into a multilayer array structure on soft substrates. The microelectrodes exhibit superior electrochemical performance for measuring electrical potentials and excellent transparency for co-localized fluorescence measurement. The device shows excellent biocompatibility

SUBMITTER: Quirion NT 

PROVIDER: S-EPMC11804930 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature