A catechol-O-methyltransferase genetic variant impacts functional movement in tactical athletes.

ABSTRACT: Functional movement is a valuable indicator of physical performance, injury risk, and/or musculoskeletal impairment following injury. However, genetic variation and gene-environment interactions that may affect functional movement are largely unexplored. We recently reported a linkage between trauma exposure and functional movement in male tactical athletes. Here, we examined the effect of a common genetic variant, rs737865, within the catechol-O-methyltransferase gene on functional movement in specialized military personnel (N = 134). We also explored whether rs737865 modulated the influence of trauma exposure. Genotyping was determined from saliva, trauma exposure was self-reported using the Brief Trauma Questionnaire, and functional movement was evaluated using the Functional Movement S

SUBMITTER: Taylor MK 

PROVIDER: S-EPMC11805364 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature