Prognostic factors in severe dengue patients: A multi-center retrospective cohort study.

ABSTRACT:

Background/purpose

Early detection of severe dengue (SD) and appropriate management are crucial in reducing the case fatality rate. The objective of this study was to investigate the clinical characteristics of SD and identify independent risk factors associated with mortality among SD patients.

Methods

A retrospective study was conducted at two medical center hospitals between 2002 and 2019, involving patients aged ≧18 years with laboratory-confirmed SD.

Results

This study included 294 patients with SD, of whom 203 (69%) survived and 91 (31%) died. Among the 294 SD patients, 103 (35%) experienced acute kidney injury, 54 (18.4%) had pneumonia, and 19 (6.5%) had bacteremia. Among the 286 patients with available alanine aminotransferase (ALT) data, 41 (14.3%) experience

SUBMITTER: Yang CH 

PROVIDER: S-EPMC11805397 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature