Presentation, management, and outcomes of central nervous system metastases in Africa: Systematic review and meta-analysis.

ABSTRACT:

Background

Central nervous system (CNS) metastases are a significant health challenge, particularly in Africa. This study evaluates the preclinical characteristics, primary causes, management strategies, and outcomes of CNS metastases in Africa.

Methods

A systematic review of the literature was conducted using PubMed, Google Scholar, and Web of Science following PRISMA guidelines to identify studies on CNS metastases in Africa.

Results

Thirty-one articles were reviewed, including 28 retrospective studies and 3 case reports. The retrospective studies comprised 12 552 patients, with 681 (5.42%) diagnosed with CNS metastases. Nigeria reported the highest number of cases (323), followed by Tunisia (180). The mean patient age was 48.20 years (range: 44.48-51.93), with a hi

SUBMITTER: O'Leary S 

PROVIDER: S-EPMC11805695 | biostudies-literature | 2025 Jan-Dec

REPOSITORIES: biostudies-literature