Alveolar socket surface area as a local risk factor for MRONJ development in oncologic patients on polypharmacy.

ABSTRACT:

Objectives

To determine the impact of alveolar socket surface area and number of root extractions for developing medication-related osteonecrosis of the jaw (MRONJ) in polypharmacy patients following multiple tooth extractions.

Materials and methods

A retrospective sample of 40 patients was recruited, including 20 polypharmacy patients (109 tooth extractions) who developed MRONJ in at least one of the extraction sites, matched with 20 controls (100 tooth extractions). Tooth-specific alveolar socket surface areas were assessed using CBCT scans from the control group to establish reference values for alveolar socket surface areas in polypharmacy patients with MRONJ. Correlations between the number of extracted tooth roots, alveolar socket surface area, and development of MRONJ

SUBMITTER: Gracea RS 

PROVIDER: S-EPMC11805769 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature