Could cleaved embryo morphology and morphokinetics be associated with prenatal and neonatal outcomes?

ABSTRACT:

Purpose

To evaluate if morphology and morphokinetics of cleaved embryos affect prenatal and perinatal outcomes.

Methods

This retrospective cohort study included 734 single fresh embryo transfer (SET) from ICSI from January 2014 to December 2020 at the Dijon University Hospital. Using time-lapse technology, embryos were defined as TOP or non-TOP according to morphological/morphokinetic criteria. Linear regression, adjusted for maternal factors, explored the association between cleaved-embryo quality and implantation rate, miscarriage rate, live birth rate, term, birthweight, and birthweight Z-score.

Results

Multivariate analyses showed that non-implanted embryos were significantly more often out of the interquartile range than implanted embryos for cell events t2 (p = 

SUBMITTER: Rey L 

PROVIDER: S-EPMC11806173 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature