Time-lapse analysis of embryos classified as euploid, mosaic, and aneuploid after embryonic trophectoderm biopsy.

ABSTRACT:

Purpose

Analyze morphokinetic, morphology, and KIDscore™Day5 in different PGT-A classes, focusing on putative mosaicism level and type.

Methods

The single-center retrospective study analyzed 832 embryoscope-cultured blastocysts from cycles with at least one putative mosaic, conducted from 2020 to 2022. A P-value < 0.05 was considered statistically significant.

Results

Putative mosaic embryos were significantly delayed compared to euploid in tPNF, t2, t4, t7, and t8 but significantly faster than aneuploid in tPNF, t2, t3, t4, t5, tSC, tM, tSB, and tB. Regarding the level, low-putative mosaic embryos (< 50%) showed significantly earlier tSC, tM, tSB, and tB compared to aneuploid, whereas high-putative mosaic embryos exhibited significantly earlier tSB and tB. Concerning

SUBMITTER: Listorti I 

PROVIDER: S-EPMC11806175 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature