Association of Adult Atopic Dermatitis with Impaired Oral Health and Oral Dysbiosis: A Case-Control Study.

ABSTRACT:

Background

Systemic alterations in the oral cavity can be reflected in skin disorders like psoriasis. However, data about oral health factors that are affected and controlled mainly by oral microbiota in atopic dermatitis (AD) are sparse. This study compared the oral status and oral microbiota of AD patients and healthy controls.

Methods

This was a prospective sex- and age-matched case-control study comparing adult participants with and without dermatologist-verified AD. A dentist assessed oral health status, and oral flora samples were collected and subjected to 16S rRNA sequencing for microbiome analysis.

Results

Forty-five AD participants and 41 non-AD controls were recruited. Compared to the participants in the control group, those with AD had significantly higher

SUBMITTER: Shahin A 

PROVIDER: S-EPMC11806328 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature