Cardiometabolic Trajectories Preceding Dementia in Community-Dwelling Older Individuals.

ABSTRACT:

Importance

Poor cardiometabolic health is a risk factor associated with cognitive impairment in later life, but it remains unclear whether cardiometabolic trajectories can serve as early markers associated with dementia.

Objective

To compare cardiometabolic trajectories that precede dementia diagnosis with those among individuals without dementia.

Design, setting, and participants

This case-control study analyzed a sample drawn from community-dwelling participants in the Aspirin in Reducing Events in the Elderly (ASPREE) study. Recruitment through primary care physicians occurred between March 2010 and December 2014, with participants followed up for a maximum of 11 years. Dementia cases were matched on sociodemographic characteristics and time of diagnosis to dementi

SUBMITTER: Wu Z 

PROVIDER: S-EPMC11806394 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature