Predictors of irritable bowel syndrome-like symptoms in quiescent inflammatory bowel disease.

ABSTRACT:

Background

Many patients with quiescent inflammatory bowel disease (IBD) suffer from irritable bowel syndrome (IBS)-like symptoms. Although these symptoms cause significant reductions in quality of life, evidence-based treatments are lacking as risk factors and pathophysiology of these symptoms are not clearly defined. We aimed to identify risk factors for development of IBS-like symptoms in IBD patients with quiescent disease.

Methods

We performed a single-center retrospective cohort study of adults with IBD from 2015 to 2021. Quiescent IBD was defined by a fecal calprotectin level <250 μg/g of stool or endoscopic evidence of quiescent disease. Cox regression was performed to identify variables that were independently associated with the incident development of IBS-like sym

SUBMITTER: Ahmed M 

PROVIDER: S-EPMC11806413 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature