Cortical lesions and focal white matter injury are associated with attentional performance in chronic traumatic brain injury.

ABSTRACT: Cognitive impairment, often due to attentional deficits, is a primary driver of disability after traumatic brain injury. It remains unclear whether attentional deficits are caused by injury to specific brain structures or the total burden of injury. In this cross-sectional, multicentre cohort study, we tested whether the association between brain injury and attentional performance varies by neuroanatomic location. Participants in the late effects of traumatic brain injury study were at least 18 years old and at least 1 year after a mild, moderate or severe traumatic brain injury. They underwent MRI and neuropsychological assessment at one of two sites. The primary and secondary outcomes, each measuring aspects of attentional performance, were the Trails A t-score and the standardize

SUBMITTER: Snider SB 

PROVIDER: S-EPMC11806419 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature