Dose-response associations of device-measured sleep regularity and duration with incident dementia in 82391 UK adults.

ABSTRACT:

Background

Sleep is a crucial lifestyle factor with impacts on mental and cognitive health. The associations between objectively measured sleep and risk of incident dementia are not yet fully understood. To evaluate the associations of device-measured sleep duration and regularity with incident dementia and explore whether sleep regularity moderates the association of sleep duration with dementia.

Methods

Population-based prospective cohort study of 82,391 adults aged 43 to 79 years from the UK Biobank accelerometry subsample, collected between 2013 and 2015, followed up to 2022. Device-based sleep duration (h/day) and sleep regularity index (SRI), a metric ranging from 0-100 that quantifies a person's sleep regularity (with a greater value indicating higher consistency), we

SUBMITTER: Bian W 

PROVIDER: S-EPMC11806617 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature