A new scheme for boosting in situ Fenton-like reaction in plant pathogenic tissues for selective structural degradation of capsid proteins.

ABSTRACT: Safe prevention and control of plant viruses is a global challenge. Inducing viral capsid protein (CP) degradation via hydroxyl radicals (∙OH) generated by an in situ Fenton-like reaction within plant pathogenic tissues is proposed for combating plant viruses in this study. We designed a new Fenton-like reaction inducer, tCu^inter-bCDs, which utilizes an internal doping strategy that reduces copper content by 89.89% compared to conventional doping methods, while still achieving a high coexistence of multivalent copper ions. Our research demonstrated that tCu^inter-bCDs possessed functional activity to specifically recognize and proximally degrade CP. tCu^inter-bCDs form complexes with CP monomers through supramolecular bonds characterized by significant electr

SUBMITTER: Ma J 

PROVIDER: S-EPMC11806622 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature