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Obesity mediates the association between psoriasis and diabetes incidence: a population-based study.


ABSTRACT:

Introduction

The aim of this study was to explore the association between psoriasis and diabetes and to assess the potential moderating role of obesity in this relationship.

Methods

The study involving data from 21,835 NHANES participants during 2003-2006 and 2009-2014. The analysis included body mass index (BMI), as well as information about psoriasis and diabetes obtained from questionnaires. The study employed weighted logistic regression to examine the association between psoriasis and diabetes. The nonlinear relationship between obesity, diabetes, and psoriasis was explored through smooth curve fitting, stratified by age and gender. In addition, the authors conducted mediation analysis, which suggested that obesity partially mediated the association between psoriasis an

SUBMITTER: Xu Z 

PROVIDER: S-EPMC11806695 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature