Advancing the accuracy of tyrosinase inhibitory peptides prediction via a multiview feature fusion strategy.

ABSTRACT: Tyrosinase plays a crucial role as an enzyme in the production of melanin, which is the pigment accountable for determining the color of the hair, eyes, and skin. Tyrosinase inhibitory peptides (TIPs), mainly designed to regulate the activity of the enzyme tyrosinase, are of interest in various domains, including cosmetics, dermatology, and pharmaceuticals, due to their potential applications in controlling skin pigmentation. To date, a few machine learning-based models have been proposed for predicting TIPs, but their predictive performance remains unsatisfactory. In this study, we propose an innovative computational approach, named TIPred-MVFF, to accurately predict TIPs using only sequence information. Firstly, we established an up-to-date and high-quality dataset by collecting samples

SUBMITTER: Shoombuatong W 

PROVIDER: S-EPMC11807091 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature