Association of statins, gliptins, and antipsychotics with bullous pemphigoid: A case-control study in the Cretan population.

ABSTRACT: Bullous pemphigoid (BP) is an autoimmune blistering disorder predominantly affecting the elderly. Recently, many studies have shed light on the effect of specific drug intake and comorbidities on the development of BP. The purpose of this study was to investigate the association of specific drug class intake and comorbidities with the development of BP in the Cretan population. Significant associations with BP were found for statins (odds ratio [OR] = 4.06, 95% confidence interval [CI] 1.99-8.27, P < 0.001), gliptins (OR = 4.27, 95% CI 2.33-7.83, P < 0.001), and antipsychotics (OR = 3.33, 95% CI 1.36-8.11, P = 0.006). Higher proportions of use in the BP group vs. control group were found for atorvastatin (OR = 1.86, 95% CI 1.04-3.32, P = 0.035), linagliptin (OR = 6.63, 95% CI 2.17-20.23, P

SUBMITTER: Kavvalou E 

PROVIDER: S-EPMC11807367 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature