Development and validation of an individualized risk prediction model for oropharynx cancer in the US population.

ABSTRACT:

Background

The incidence of oropharynx cancers has increased substantially in the United States. However, risk stratification tools for the identification of high-risk individuals do not exist. In this study, an individualized risk prediction model was developed and validated for oropharynx cancers in the US population.

Methods

A synthetic, US population-based case-control study was conducted. Oropharynx cancer cases diagnosed at Ohio State University (n = 241) were propensity-weighted to represent oropharynx cancers occurring annually in the United States during 2009-2014 (n = 12,656). Controls (n = 9327) included participants in the National Health and Nutrition Examination Survey (2009-2014) and represented the annual US population aged 30 to 69 years (n = 154,532,508). T

SUBMITTER: Tota JE 

PROVIDER: S-EPMC11807415 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature