Exploring the association between pro-inflammatory diets and chronic liver diseases: evidence from the UK Biobank.

ABSTRACT:

Background

Chronic liver diseases (CLD) continue to pose a significant global burden, potentially exacerbated by pro-inflammatory diets. This study explores the relationship between the Dietary Inflammatory Index (DII), a measure of dietary inflammatory potential, and CLD risk.

Methods

Utilizing data from the UK Biobank cohort, we assessed the dietary information and calculated the DII for each participant. Cox proportional hazards models and Fine-Gray competing risk models were employed to evaluate the association between DII and CLD incidence, adjusting for potential confounders.

Results

Our analysis included 121,329 participants with a median follow-up of 604.43 weeks, during which 4,018 developed CLD. A higher DII, indicating a more inflammatory diet, was associat

SUBMITTER: Pan L 

PROVIDER: S-EPMC11807818 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature