Characterisation of phenotypic patterns in equine exercise-associated myopathies.

ABSTRACT:

Background

Equine exercise-associated myopathies are prevalent, clinically heterogeneous, generally idiopathic disorders characterised by episodes of myofibre damage that occur in association with exercise. Episodes are intermittent and vary within and between affected horses and across breeds. The aetiopathogenesis is often unclear; there might be multiple causes. Poor phenotypic characterisation hinders genetic and other disease analyses.

Objectives

The aim of this study was to characterise phenotypic patterns across exercise-associated myopathies in horses.

Study design

Historical cross-sectional study, with subsequent masked case-control validation study.

Methods

Historical clinical and histological features from muscle samples (n = 109) were used for k-mea

SUBMITTER: Lindsay-McGee V 

PROVIDER: S-EPMC11807944 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature