Exploring the association between tissue sodium content, heart failure subtypes, and symptom burden: insights from magnetic resonance imaging.

ABSTRACT:

Aims

Heart failure (HF) is a complex clinical syndrome with high morbidity and mortality, influenced significantly by sodium balance. Recently, magnetic resonance imaging (MRI) has emerged as a non-invasive method to evaluate tissue sodium load in HF patients. This proof-of-principle study investigates the association between tissue sodium content, assessed by MRI, and HF-related baseline parameters in an outpatient cohort of patients with chronic heart failure, including those with reduced ejection fraction (HFrEF), mildly reduced ejection fraction (HFmrEF), and preserved ejection fraction (HFpEF).

Methods and results

This prospective study included 29 HF patients (10 HFpEF, 12 HFmrEF, and 7 HFrEF) recruited from two centers in Berlin, Germany. Patients underwent MRI to ass

SUBMITTER: Hashemi D 

PROVIDER: S-EPMC11807970 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature