Associations of maternal PM2.5 exposure with preterm birth and miscarriage in women undergoing <i>in vitro</i> fertilization: a retrospective cohort study.

ABSTRACT:

Background

Excessive exposure to PM2.5 can be detrimental to reproductive health. The objective of this study was to investigate the potential associations between ambient PM2.5 exposure during different periods and negative pregnancy outcomes, such as miscarriage and preterm birth, in patients who underwent assisted reproductive technology (ART).

Methods

This retrospective cohort study examined the outcomes of 2,839 infertile women aged ≤ 45 years who underwent their first fresh or frozen-thawed embryo transfer at the Shanghai First Maternity and Infant Hospital between April 2016 and December 2019. Satellite data were used to determine the daily average levels of PM2.5, and exposure was categorized as excessive if it exceeded the WHO's interim target 2 level of 50 µg/m

SUBMITTER: Chen M 

PROVIDER: S-EPMC11808209 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature