Can Coenzyme Q10 Supplementation Reduce Cardiovascular Disease Risk Factors? A Protocol for a GRADE-Assessed Systematic Review and Dose-Response Meta-Analysis of Randomized Controlled Trials.

ABSTRACT:

Background and aims

Cardiovascular diseases (CVDs), encompassing a variety of conditions affecting the heart and blood vessels, remain a significant global public health challenge. Among various therapeutic options, Coenzyme Q10 (CoQ10) has garnered attention due to its potential benefits for cardiovascular health. CoQ10 is a naturally occurring antioxidant that plays a crucial role in cellular energy production and has long been used therapeutically. This study aims to summarize and systematically analyze the scientific literature on glycemic profile, lipid profile, anthropometric measures, blood pressure, inflammatory factors, liver function tests, oxidative stress parameters and adipokines associated with CoQ10 supplementation to provide a basis for clinical treatment.

Method

SUBMITTER: Jafari A 

PROVIDER: S-EPMC11808257 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature