OPTO: Automated Optimization for Solid-State NMR Spectroscopy.

ABSTRACT: NMR spectroscopy presents boundless opportunities for understanding the structure, dynamics, and function for a broad range of scientific applications. Solid-state NMR (SSNMR), in particular, provides novel insights into biological and material systems that are not amenable to other approaches. However, a major bottleneck is the extent of user training and the difficulty of obtaining reproducible, high-quality experimental results, especially for the sophisticated multidimensional pulse sequences that are essential to provide site-resolved measurements in large biomolecules. Here, we present OPTO, a software operating environment that addresses these challenges and enhances the performance of many types of commonly utilized SSNMR experiments. OPTO is compatible with Varian OpenVnmrJ and Br

SUBMITTER: Borcik CG 

PROVIDER: S-EPMC11808819 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature