The prevalence of frailty according to kidney function and its association with cognitive impairment, nutritional status, and clinical outcome.

ABSTRACT:

Background

Frailty is a state of vulnerability to poor homeostatic resolution of after a stressful event. The prevalence of frailty in patients with chronic kidney disease (CKD) is more common than in the general population. Frailty is associated with a poor clinical prognosis, malnutrition, and cognitive impairment; however, studies on these factors in patients with CKD are lacking. Therefore, we aimed to evaluate the relationship between CKD and frailty, nutritional status, and cognitive impairment and their influence on clinical outcomes.

Methods

We prospectively enrolled participants from June 2019 to December 2020 and divided them into three CKD groups according to kidney function (CKD G1-2, CKD G3-4, and CKD G5D). Clinical outcomes were defined as the composite outcome

SUBMITTER: Yang TW 

PROVIDER: S-EPMC11808967 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature