MiR398 targets a Cu²⁺-containing Selenium Binding Protein (SBP) in rice and the phylogenetic analysis of the miR398-SBP module in plants.

ABSTRACT:

Background

MicroRNA 398 (miR398), one of the conserved miRNAs, is known to target multiple genes encoding Cu²⁺-containing proteins such as the conserved two Cu/Zn Superoxide dismutases (CSD1 and CSD2) and a Cu²⁺-chaperone for CSDs (CCS) as primary targets. Additionally, miR398 is known to target transcripts of Cu²⁺-containing proteins such as cytochrome C-oxidase, Cupredoxin, and blue copper binding protein (BCBP) that are poorly conserved among plants.

Results

Our recently generated rice degradomes have validated Selenium Binding Protein (SBP), yet another Cu²⁺-containing protein, as a genuine target of miR398. Because SBP was largely underappreciated target of miR398, we sought to uncover potential conservation of miR398-SBP regu

SUBMITTER: Payne D 

PROVIDER: S-EPMC11809012 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature