The double-edged sword of statins in intracerebral hemorrhage patients: a systematic review and meta-analysis.

ABSTRACT:

Background

This meta-analysis aimed to investigate the effect of statins on the prognosis of patients with intracerebral hemorrhage (ICH).

Methods

We conducted a systematic search using the keywords "statin" and "intracerebral hemorrhage" across four electronic databases (PubMed, Cochrane Library, Web of Science, and Embase) from their inception to October 31, 2023, to identify studies comparing the effects of statins on the prognosis of patients with ICH. The primary outcome was total mortality after ICH. This meta-analysis was registered online (PROSPERO ID: CRD42023493063).

Results

Our initial search identified 5,543 studies. After applying inclusion criteria, 30 studies with a total of 42,298 patients were included in the final analysis. Our meta-analysis showed t

SUBMITTER: Li Z 

PROVIDER: S-EPMC11809033 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature