Impact of maternal lipid profiles on offspring birth size in late pregnancy among women with and without gestational diabetes.

ABSTRACT:

Background

Maternal glucose and lipid levels are known to influence fetal growth. However, data on how maternal lipid profiles affect birth size in women with gestational diabetes (GDM) compared with those without GDM are scarce.

Methods

This retrospective study included 10,490 women with singleton pregnancies (2351 with GDM and 8139 without GDM) between December 2016 and July 2022. Maternal serum levels of total cholesterol (TC), triglycerides (TGs), low-density lipoprotein (LDL) cholesterol, and high-density lipoprotein (HDL) cholesterol were measured at 28-42 weeks of gestation. Maternal glucose levels were determined using the 2-h oral glucose tolerance test. The neonatal birth weight was obtained at delivery and standardized as the birth weight z score according to the

SUBMITTER: Peng J 

PROVIDER: S-EPMC11809092 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature